Okay, we are basically being asked to do implicit differentiation here and recall that we are assuming that $z$ is in fact $z\left( {x,y} \right)$ when we do our derivative work.

Let’s get $\frac{{\partial z}}{{\partial x}}$ first and that requires us to differentiate with respect to $x$. Just recall that any product involving $x$ and $z$ will require the product rule because we’re assuming that $z$ is a function of $x$. Also recall to properly chain rule any derivative of $z$ to pick up the $\frac{{\partial z}}{{\partial x}}$ when differentiating the “inside” function.

Differentiating the equation with respect to $x$ gives,

$$2x\sin \left( {{y^3}} \right) + {{\bf{e}}^{3z}} + 3\frac{{\partial z}}{{\partial x}}x{{\bf{e}}^{3z}} + 2z\frac{{\partial z}}{{\partial x}}\sin \left( {{z^2}} \right) = - 6\frac{{\partial z}}{{\partial x}}$$

Solving for $\frac{{\partial z}}{{\partial x}}$ gives,

$$2x\sin \left( {{y^3}} \right) + {{\bf{e}}^{3z}} = \left( { - 6 - 3x{{\bf{e}}^{3z}} - 2z\sin \left( {{z^2}} \right)} \right)\frac{{\partial z}}{{\partial x}}\hspace{0.5in} \to \hspace{0.5in} \require{bbox} \bbox[2pt,border:1px solid black]{{\frac{{\partial z}}{{\partial x}} = \frac{{2x\sin \left( {{y^3}} \right) + {{\bf{e}}^{3z}}}}{{ - 6 - 3x{{\bf{e}}^{3z}} - 2z\sin \left( {{z^2}} \right)}}}}$$ Show Step 2